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Denton Cooley
American cardiologist Denton Cooley is the
surgeon who performed the world’s first implantation of a total artificial
heart. During the 1960s the techniques of human heart transplant were still in
their infancy and at such a time he implanted an artificial heart into a
patient when a real human heart was unavailable. This artificial heart helped
to keep the patient alive for the 64 hours before a donor heart became
available. As a heart surgeon he worked closely with the brilliant senior
cardiologist, Michael DeBakey, but the fact that Cooley performed the
artificial heart implantation without DeBakey’s supervision created a rift
between the two. As a young boy Cooley wanted to be a dentist but changed his
mind later on as he grew fascinated with the human heart. He studied medicine
at Johns Hopkins in Baltimore where he found a mentor in the experienced
doctor, Dr. Alfred Blalock. Having grown up with an alcoholic father, Cooley
found in Dr. Blalock a father figure he had sorely missed as a youngster. Under
his guidance the hitherto shy and insecure boy thrived and went on to become
one of the 20th century pioneers in cardiac surgery. In spite of his hectic schedule
he remains a devoted family man and loves to play golf in his free time.
Childhood & Early
Life
· He was born on August 22, 1920 in Texas. His
father was a successful dentist and had a thriving practice; thus the family
lived comfortably even during the Great Depression when others were struggling.
However, his father was also an alcoholic and thus Denton had a complicated
relationship with him.
· As a young boy he was shy and insecure but he
blossomed into a confident person when he went to school. He was a brilliant
student who excelled in academics and also did well in sports.
· He enrolled at the University of Texas where
he majored in zoology and also played for the college basketball team.
· Initially he aspired to become a dentist but
later decided to pursue medicine. He began his medical education at University
of Texas Medical Branch in Galveston before transferring to Johns Hopkins
School of Medicine in Baltimore, Maryland. At John Hopkins he met Dr. Alfred
Blalock who became his mentor.
· He considered Dr. Blalock to be a pioneer in
cardiology and resolved to follow in his footsteps. He obtained his M.D. degree
in 1944 and assisted Dr. Blalock in correcting an infant’s congenital heart
defect, an operation known as “Blue Baby” procedure.
Career
§ He joined the Army Medical Corps in 1946 and
served as chief of surgical services at the station hospital in Austria. After
two years he was discharged with the rank of captain in 1948.
§ After the World War II, he returned to Hopkins
to complete his residency after which he remained there as an instructor in
surgery. He went to London in 1950 to work with the eminent British surgeon,
Lord Russell Brock.
§ During the 1950s he moved to Houston to accept
a position as the associate professor of surgery at Baylor College of Medicine.
He also worked at its affiliate institution, the Methodist Hospital.
§ The decade of 1950s also saw Cooley working
with Dr. Michael E. DeBakey, an eminent cardiologist and a few years senior to
Cooley. The two men, both exceptionally brilliant at their chosen field had a
tumultuous relationship as their egos often clashed.
§ Cooley along with his colleagues worked on
developing artificial heart valves over the 1960s. His work on artificial heart
valves helped to bring down the mortality for heart valve transplants from 70%
in 1962 to 8% in 1967.
§ He performed his first human heart transplant
in May 1968, just months after Dr. Christiaan Barnard had performed the world’s
first successful human heart transplant.
§ In 1969, he implanted an artificial heart in a
human being for the first time. The patient, Haskell Karp lived for 64 hours
with the implanted device before it could be replaced with a donor’s heart. The
patient however died a day after the second operation and questions were raised
about the doctor’s decision to implant the artificial device in the first
place.
§ The incident of Cooley implanting an
artificial heart in a patient was severely criticized by Dr. DeBakey and the
relationship between the two doctors was strained beyond repair. Thus Cooley
resigned from his post at Baylor.
§ Cooley was a prolific surgeon and by 1972 he
had performed over 1200 bypass surgeries and 10,000 open-heart operations—a
world record for a cardiac surgeon.
§ The Denton A. Cooley Cardiovascular Surgical
Foundation was established by the Residents and Fellows of Cooley in his honor
in 1972. Today over 900 cardiac surgeons from countries all over the world are
members of this prestigious organization.
Major Works
§ Denton Cooley created history in April 1969
when he implanted an artificial heart in a 47-year-old man, Haskell Karp who
was dying of a heart condition. This mechanical heart kept Karp alive for 64
hours before a donor heart could be transplanted. Though the patient did not
live for long after surgery, this implantation still remains a medical
breakthrough.
Awards &
Achievements
§ The International
Surgical Society awarded him the Renée Lebiche Prize—its highest honor—in 1967,
calling him "the most valuable surgeon of the heart and blood vessel
anywhere in the world."
§ In 1984 former
President Ronald Reagan presented Cooley with the US’s highest civilian award,
the National Medal of Freedom for his great contributions to the field of
medical science.
§ President Bill Clinton
presented him with the National Medal of Technology—the highest honor for
technological innovation in the US—in 1998.
Personal Life &
Legacy
§ He married Louise
Goldborough Thomas, a registered nurse, in 1949. The couple was blessed with
five daughters. Today, he also has several grandchildren.
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